Human Low-density lipoprotein receptor-related protein 2 (LRP2) ELISA Kit,Abbkine_specification/price/image

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LRP2 is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins.

Human Low-density lipoprotein receptor-related protein 2 (LRP2) ELISA Kit employs a two-site sandwich ELISA to quantitate LRP2 in samples. An antibody specific for LRP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyLRP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LRP2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LRP2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Low-density lipoprotein receptor-related protein 2 (LRP2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-low-density-lipoprotein-receptor-related-protein-2-lrp2-elisa-kit-kte61783/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.