Human Low-density lipoprotein-receptor-related protein 4 (LRP-4) ELISA Kit,Abbkine_specification/price/image

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Proteins with EGF-like domains often consist of more than 1,000 amino acids, have multiple copies of the EGF-like domain, and contain additional domains known to be involved in specific protein-protein interactions. The predicted partial LRP4 protein contains 2 EGF-like domains, a calcium binding-type EGF-like domain, 3 LDL receptor-type EGF-like domains, 4 YWTD spacer regions, a transmembrane domain, a cytoplasmic NPXY motif, which is required for clustering and internalization of LDL receptors, and a cytoplasmic tSXV motif, which anchors proteins with a PDZ domain. The sequence and domain organization of LRP4 shows significant similarities to those of members of the LDL receptor family. Northern blot analysis detected rat Megf7 expression in several regions of the brain.

Human Low-density lipoprotein-receptor-related protein 4 (LRP-4) ELISA Kit employs a two-site sandwich ELISA to quantitate LRP4 in samples. An antibody specific for LRP4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyLRP4 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LRP4 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LRP4 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Low-density lipoprotein-receptor-related protein 4 (LRP-4) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-low-density-lipoprotein-receptor-related-protein-4-lrp-4-elisa-kit-kte61782/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.