MMP24 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase).
Human Matrix metalloproteinase-24 (MMP24) ELISA Kit employs a two-site sandwich ELISA to quantitate MMP24 in samples. An antibody specific for MMP24 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMMP24 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MMP24 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MMP24 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Matrix metalloproteinase-24 (MMP24) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-matrix-metalloproteinase-24-mmp24-elisa-kit-kte61592/
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