Lonza Reveals New Portfolio of Hepatocytes for ADME-Tox Testing

Lonza Reveals New Portfolio of High-Quality Human and Animal Hepatocytes for ADME-Tox Testing 

 

Cologne, Germany / Basel, Switzerland, 16 March 2017 – Lonza now offers a comprehensive portfolio of fresh and cryopreserved human and animal hepatocytes for ADME-Tox testing, further strengthening its position as a leader in cell discovery. This expansion of Lonza’s primary cells range is the result of last year’s acquisition of renowned hepatocyte provider, Triangle Research Laboratories (TRL). By combining TRL’s expertise with Lonza’s quality control, large production capacity and scientific support, Lonza can now provide a source of high-quality hepatocytes for in-vitro drug metabolism and pharmacokinetic studies or for vital research into diseases such as Malaria and Hepatitis B.

 

Lonza’s new range of ADME-Tox products includes both fresh and cryopreserved human and animal hepatocytes, supporting researchers with a variety of in-vitro applications, including studies into drug metabolism and toxicity, drug-transporter activity and drug-drug interactions. The new hepatocyte portfolio also features hepatic non-parenchymal cells, such as stellate and Kupffer cells, which can improve the translatability of in-vitro toxicity testing and pharmacokinetics research to clinical trials.

Lonza’s hepatocytes are pre-qualified for a variety of different applications, which helps to reduce time and money spent evaluating cells for specific experiments within the laboratory. The new range also includes supporting ADME-Tox products such as specialized hepatocyte media and cell culture systems, helping to optimize hepatocyte culture performance for in-vitro drug screening or for research into drug-induced liver injury and other important liver diseases.

 

“With many conclusions regarding the pharmacokinetics and safety of a drug candidate being drawn from the results of in-vitro studies on human hepatocytes, researchers need a source of hepatocytes they can rely on,” said Maureen Bunger, Product Manager for ADME-Tox Solutions at Lonza. “By blending the extensive expertise of Lonza and TRL, our new hepatocyte portfolio will address the needs of the scientific community, offering hepatocytes that produce consistent and reliable results for ADME-Tox testing and for research into liver-associated diseases.”

 

For more information about Lonza’s hepatocyte portfolio, please visit: http://www.lonza.com/products-services/bio-research/adme-tox.aspx

 

About Lonza

Lonza is one of the world’s leading and most-trusted suppliers to the pharmaceutical, biotech and specialty ingredients markets. It harnesses science and technology to create products that support safer and healthier living and that enhance the overall quality of life.

 

Not only is Lonza a custom manufacturer and developer, the company also offers services and products ranging from active pharmaceutical ingredients to drinking water sanitizers, from nutritional and personal care ingredients to agricultural products, and from industrial preservatives to microbial control solutions that combat dangerous viruses, bacteria and other pathogens.

 

Founded in 1897 in the Swiss Alps, Lonza today is a well-respected global company with approximately 40 major manufacturing and R&D facilities and more than 10,000 full-time employees worldwide. The company generated sales of CHF 4.13 billion in 2016 and is organized into two market-focused segments: Pharma&Biotech and Specialty Ingredients. Further information can be found at www.lonza.com.

 

Lonza Contact Information

 

Lonza Cologne GmbH	Lonza Group Ltd	Lonza Group Ltd
Manager Marketing Communications	Head Corporate Communications	Head External Communications
Petra Haberkamm	Dominik Werner	Constance Ward
Tel +49 221 991990	Tel +41 61 316 8798	Tel +41 61 316 8840
Fax +49 221 99199498	Fax +41 61 316 9540	Fax +41 61 316 9840
marcom.lbs@lonza.com	dominik.werner@lonza.com	constance.ward@lonza.com