The recombinant human IL-17 protein is expressed in E. coli, whose amino acid sequence is derived from mature form of human IL17A (Q16552), (Ile20-Ala155) was expressed, with a N-terminal Met.

The recombinant human IL17A consists of 137 amino acids and predicts a molecular mass of 15.7 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions.

Human IL-17 protein measured by its ability to induce IL-6 secretion by HFF human foreskin fibroblast cells. The ED50 for this effect is typically 15-75 ng/mL.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.