The recombinant human Latent TGF-beta 1 protein, His Tag is expressed in Human Cells, whose amino acid sequence is derived from full length of human TGFβ1 (NP_000651.3), (Met 1-Ser 390) was fused with a C-terminal polyhistidine tag.

The recombinant human latent TGFβ1 consists of 370 amino acids and has a calculated molecular mass of 42.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh TGFβ1 is approximately 16, 38 and 55 kDa corresponding to mature TGFβ1, LAP protein and inacitve latent TGFβ1 respectively due to glycosylation. In non-reduced SDS-PAGE, it migrates as an approximately 110 kDa protein consisting of a TGFβ1 homodimer non-covalently linked to a LAP homodimer.

Human Latent TGF-beta 1 protein, His Tag measured by its ability to bind biotinylated Human ALK1-Fc (Cat:10066-H02H) in functional Elisa.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.