The recombinant human IL-35 (IL-12A & IL-27B) protein, Fc Tag is expressed in Human Cells, whose amino acid sequence is derived from human IL35 complex composed of IL27B subunit (NP_005746.2), (Met 1-Lys 229) and the mature form of human IL12 p35 subunit (P29459) (Arg 23-Ser 219) linked by a polypeptide linker was fused with the Fc region of human IgG1 at the C-terminus.

The recombinant human IL35/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 645 amino acids and has a predicted molecular mass of 73.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhIL35/Fc monomer is approximately 90-100 kDa due to glycosylation.

Human IL-35 (IL-12A & IL-27B) protein, Fc Tag measured by its ability to bind biotinylated human IL6RB-Fch (Cat:10974-H03H) in a functional ELISA.

Abbkine suplies sizes: 20µg, 50µg of Human IL-35 (IL-12A & IL-27B) protein, Fc Tagfor your choice, more detailed information at https://www.abbkine.com/product/human-il-35-il-12a-&-il-27b-protein-fc-tag-prp100184.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.