Creative Biolabs provides various techniques such as flow cytometry-based FRET, immunoprecipitation and western blotting for TCR pairing assay. Mispaired TCR heterodimers may result in the diluted expression of TCR transgene or the generation of autoreactive TCR, which affect the efficacy and safety of TCR engineered T cell therapy subsequently. It is a challenge to optimize TCR pairing issue. Creative Biolabs' various methods of to assess TCR pairing and evaluate efficacy and safety of TCR transfer.
https://www.creative-biolabs.com/car-t/tcr-pairing.htmbio-equip.cn
Creative Biolabs is the leading custom service provider that has extensive experience in various antibody production and engineering fields. Our service portfolio includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit,chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies [including phage display, bacterial display and yeast display]. We are also professional in conducting in depth antibody humanization and affinity maturation usingphage display and DNA mutagenesis approaches. In addition, OEM services for bulk scale antibody manufacturing, including bacterial production of scFv, diabody, tandem scFv, miniantibody and Fab, and mammalian cell expression of minibody, chimeric IgG and IgG, are also available at the most competitive price in the industry.
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