Protein kinase represents an important family of target in drug development. The success of recently approved kinase inhibitors has proved the value of targeting kinases in cancer treatment. Despite the great progress in developing reagents and assays to measure kinase activity with purified proteins, questions remain about whether these methods can deliver sensitive, robust and accurate results. Unlike in vitro assays, cell-based methods provide direct information of how drug molecules truly interact with kinases in the presence of myriad known or unknown cellular factors, resulting in more reliable and relevant data.

For years, Profacgen has gleaned valuable experience from studies of numerous biological targets and systems. To meet the growing demand in kinase study, we are now offering a novel platform to evaluate cell-based activity of drug candidates with a focus on a comprehensive set of critical parameters. At Profacgen, cell-based kinase assays are offered in two ways:

https://www.profacgen.com/cell-based-kinase-assays.htm

Profacgen offers a full range of biopharmaceutical development and bio-manufacturing services that cover strategic consultancy, world-class process development, cGMP manufacturing, and analytical development.