Profacgen is an expert in the field of studying protein-nucleic acid interactions. We can now provide a new and powerful technique CUT&RUN-sequencing, which is also known as cleavage under targets and release using nuclease. CUT&RUN-sequencing can be used to map global DNA binding sites accurately for any target proteins.

Genome sequence has been studied over a decade, but our knowledge of genome still need much exploration. Chromatin structure determines to function of DNA, which involves in regulating accessibility to transcription factors and other DNA-interacting proteins. Currently the most wildly used technique for the investigation of DNA-protein interaction is ChIP-sequencing, but it suffers from many restrictions. CUT&RUN-sequencing is a development and replacement of ChIP-seq technique since it is cost-effective and simple to perform.

https://www.profacgen.com/cut-run-sequencing-service.htm