Exposure experiments are widely used in toxicology, pharmacodynamics and pharmacokinetic studies, animal modeling and other experiments, and the experimental results are widely regarded as an important index for toxicity evaluation of various drugs, molecules, particles and so on. Exposure tests include whole body exposure, head exposure, nose-only inhalation exposure, intratracheal exposure and so on. Compared with
other exposure methods, oral and nasal inhalation exposure effectively avoids or restricts various nonrespiratory intake pathways of various drugs. It is especially suitable for the study of inhaled pathotoxicology, respiratory diseases and other fields.
The features of the inhalation exposure system：
· The specified exposure concentration can be achieved by minimizing the drug dose.
· Avoid other non-respiratory intake pathways.
· Eliminate potential eye irritation and other effects on animals.
· The exposure dose of each animal can be accurately controlled.
· High-throughput, very suitable for large-scale experiments such as drug screening.
Product introduction：
NIES (Nose-Only Inhalation Exposure System) of Yuyan instrument takes the imported advanced instrument as the prototype, highly restore the nose-only inhalation design principle, exquisite design, efficient and stable performance, high performance-to-price ratio. The equipment is specially designed for rodents. It has the original imported atomization device, the atomized particles are very fine, the aerosol output is stable, and different forms of aerosol output such as dust, liquid, aromatherapy and cigarette smoke can be selected according to different experimental needs.The main body of the instrument is made of stainless steel, excellent workmanship, high-quality rubber sealing ring to ensure excellent air tightness and reduce damage to laboratory personnel.The unique circulation ventilation function ensures that the drug concentration is stable and fresh, and promotes the timely emission of waste gas at the same time. Comfortable animal adapters make the environment of experimental animals more comfortable.
Composition of the system：
Exposure tower: Stainless steel, corrosion resistant; 8 channels per layer, stackable upgrade design for easy disassembly and cleaning; double-layer gas transport channels, different animal suction and exhalation channels to ensure gas freshness and drug exposure uniformity; exposure chamber conforms to animal engineering design, animal comfort is strong, in line with animal welfare.
Waste gas recovery: active waste gas recovery device, which can absorb and filter animal breathing waste gas at a specific rate, make the waste gas meet the emission safety standards, and reduce the damage to laboratory personnel and the environment.
Aerosol atomization and observation module: the original imported atomization device, jet atomization, the use of compressed air through the small pipe mouth of highspeed air flow to drive the solution to spray high-speed impact to form aerosol, the atomized particles formed in this way are very fine, and are not easy to collide and combine, inhaled comfortably, and can reach the deep lung tissue directly.
In addition, there are drug delivery devices, a variety of gas pipelines and so on.
More collocation options：
In addition to the above products, the system can also be equipped with particle concentration detection devices, lung function testing devices to form a comprehensive respiratory exposure solution, please call for details.
Manufacturer: Shanghai Yuyan Instruments Co, Ltd.
Country of Origin:China
CONTACT INFORMATION
Shanghai Yuyan Instruments Co, Ltd.
Address: Room 506, XingMei Rd 485, Shanghai, 201100, China
Email:yuyanbio@vip.163.com
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