Malignant T cell-amplified sequence 1 (MCTS1) is an anti-oncogene that plays a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition. When constitutively expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.
Chicken Malignant T cell-amplified sequence 1 (MCTS1) ELISA Kit employs a two-site sandwich ELISA to quantitate MCTS1 in samples. An antibody specific for MCTS1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMCTS1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MCTS1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MCTS1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Chicken Malignant T cell-amplified sequence 1 (MCTS1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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