LDLR chaperone MESD (MESDC2) is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
Chicken LDLR chaperone MESD (MESDC2) ELISA Kit employs a two-site sandwich ELISA to quantitate MESDC2 in samples. An antibody specific for MESDC2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMESDC2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MESDC2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MESDC2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Chicken LDLR chaperone MESD (MESDC2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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