MTMR8 encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases.
Chicken Myotubularin-related protein 8 (MTMR8) ELISA Kit employs a two-site sandwich ELISA to quantitate MTMR8 in samples. An antibody specific for MTMR8 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMTMR8 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MTMR8 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MTMR8 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Chicken Myotubularin-related protein 8 (MTMR8) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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