Chicken Transforming growth factor β2 (TGF-β2) ELISA Kit,Abbkine_specification/price/image

Product Detail
Company Profile

TGF-β2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes TGF-β2 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in TGF-β2 may be associated with Loeys-Dietz syndrome. TGF-β2 encodes multiple isoforms that may undergo similar proteolytic processing.

Chicken Transforming growth factor β2 (TGF-β2) ELISA Kit employs a two-site sandwich ELISA to quantitate TGFB2 in samples. An antibody specific for TGFB2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTGFB2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TGFB2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TGFB2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Chicken Transforming growth factor β2 (TGF-β2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.