NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. NFKB inhibitor alpha interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. NFKB inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in NFKBIA have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
The Abbkine IκB-α (phospho Ser32/S36) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of IκB-α protein only when phosphorylated at S32/S36. The antibody has been validaed in WB, IHC-P, IF, ELISA and reacts with Human, Mouse, Rat, Monkey samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-IκB-α (phospho Ser32/S36) Polyclonal Antibody at https://www.abbkine.com/product/iκb-α-phospho-ser32-s36-polyclonal-antibody-abp50346.
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