BCL2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
The Abbkine Bcl-2 (phospho Ser70) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of Bcl-2 protein only when phosphorylated at S70. The antibody has been validaed in WB, IHC-P, IP, ELISA and reacts with Human, Monkey samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Bcl-2 (phospho Ser70) Polyclonal Antibody at https://www.abbkine.com/product/bcl-2-phospho-ser70-polyclonal-antibody-abp50273.
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