Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H2AFX encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
The Abbkine Histone H2A.X (Acetyl Lys5) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen and detects endogenous Histone H2A.X (Acetyl Lys5) protein. The antibody has been validaed in WB and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Histone H2A.X (Acetyl Lys5) Polyclonal Antibody at https://www.abbkine.com/product/histone-h2a.x-acetyl-lys5-polyclonal-antibody-abp50245.
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