Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFZ encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
The Abbkine Histone H2A).Z (Acetyl Lys7) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen and detects endogenous Histone H2A.Z (Acetyl Lys7) protein. The antibody has been validaed in WB and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Histone H2A.Z (Acetyl Lys7) Polyclonal Antibody at https://www.abbkine.com/product/histone-h2a.z-acetyl-lys7-polyclonal-antibody-abp50230.
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