PTGS1 is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Prostaglandin-endoperoxide synthase 1 regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, prostaglandin-endoperoxide synthase 1 has been identified as a moonlighting protein. Prostaglandin-endoperoxide synthase 1 may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
The Abbkine COX1 Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen and detects endogenous COX1 proteins. The antibody has been validaed in WB and reacts with Human samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-COX1 Polyclonal Antibody at https://www.abbkine.com/product/cox1-polyclonal-antibody-abp50159.
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