KIF7 encodes a cilia-associated protein (kinesin family member 7) belonging to the kinesin family. Kinesin family member 7 plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in KIF7 have been associated with various ciliopathies.
The Abbkine Kif 7 Mouse Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen and detects endogenous Kif 7 proteins. The antibody has been validaed in IHC-P, IF and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Kif 7 Monoclonal Antibody at https://www.abbkine.com/product/kif-7-monoclonal-antibody-abm40063.
bio-equip.cn
中文
