The protein encoded by PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. proliferating cell nuclear antigen acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, proliferating cell nuclear antigen is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.
The Abbkine PCNA Mouse Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen and detects endogenous PCNA protein. The antibody has been validaed in WB, IF, IHC-P and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-PCNA Monoclonal Antibody at https://www.abbkine.com/product/pcna-monoclonal-antibody-abm40031.
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