HMGB1 encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. High mobility group box 1 plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of HMGB1 have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
The Abbkine HMG-1 (Acetyl Lys12) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of HMG-1 protein only when non-acetylation at K12. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-HMG-1 (Acetyl Lys12) Polyclonal Antibody at https://www.abbkine.com/product/hmg-1-acetyl-lys12-polyclonal-antibody-abp50136.
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