TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that TP73 is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for TP73, but the biological validity and the full-length nature of some variants have not been determined.
The Abbkine p73 (Acetyl Lys321) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen anddetects endogenous levels of p73 protein only when acetylated at K321. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-p73 (Acetyl Lys321) Polyclonal Antibody at https://www.abbkine.com/product/p73-acetyl-lys321-polyclonal-antibody-abp50113.
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