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- RB1 FISH Probe
- Product Detail
- Company Profile
The RB1 gene is a well characterized tumor-suppressor gene; bi-allelic inactivation of the RB1 gene due to mutations and/or deletions is causal for the development of Retinoblastoma (RB). Deletions of the RB1 locus are also common in a wide variety of solid tumors and hematologic malignancies including chronic lymphocytic leukemia, multiple myeloma, acute myelocytic leukemia, myelodysplastic syndrome, and chronic myeloproliferative disorders.
Empire Genomics has developed a custom RB1 probe which can be used to detect/confirm a rearrangement of the RB1 gene. The probe comes labeled in orange, and generally ships within 24 hours. You can choose to customize the probe to meet your needs, which will ship right after production of the probe is complete (approximately 1 week).Probe Details
Gene:
RB1 (Orange 5-TAMRA dUTP)
Loci:
13q14
Test Kits:
20
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The leading supplier of molecular diagnostics for customization and production of FISH probes, aGCH assays and upcoming new technologies to be used by Reference labs, Academic labs, Pharma, CRO’s
and Pharma /Biotech companies around the world.
Our companion Diagnostics will allow you to :
-Validate Bio-markers (signature identification and resistance).
-Identify and qualify the aberration at the Chromosomal level of specific population.
-Follow up the result of therapeutic treatment (monitoring, compound profiling, drug response, patient stratification and safety)
-Compare with the result of your current technology.
-Be translated into the initial phase of your diagnostics development toward new FDA filings (pre-clinical through clinical trial development).
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