Deletion of chromosome 13q14.3 occurs in multiple myeloma, non-Hodgkins lymphoma, chronic lymphocytic leukemia, myeloproliferative disorders, myelodysplastic syndrome, and acute nonlymphocytic leukemia. The D13S319 Fluorescence In Situ Hybridization (FISH) probe is useful in detecting deletions in a higher percentage of cells than by routine cytogenetic studies. The probe can be used to evaluate complex karyotypes for loss of this critical gene region.
Empire Genomics has developed a custom D13S319 probe which can be used to detect/confirm a rearrangement of the D13S319 gene. The probe comes labeled in orange, and generally ships within 24 hours. You can choose to customize the probe to meet your needs, which will ship right after production of the probe is complete (approximately 1 week).
Probe Details
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Gene: |
D13S319 (Orange 5-TAMRA dUTP) |
Loci: |
13q14 |
Test Kits: |
20 |