Finally! The Symphony you've been waiting for! The Symphony X comes with twice the number of reaction vessels as the original Symphony, extra amino acid and bottle positions, flexible fluid deliveries and more! Run different sequences, scales and protocols on multiple reactors all at the same time! Start, Stop or Pause reactors whenever you wish! It's like having 24 synthesizers in one! Or, run up to 12 reaction vessels with preactivation! Also comes with optional UV-monitoring! With all this and more, the Symphony X is the perfect platform for R&D, protocol optimization or production!
Specifications:
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Synthesis Scale:
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0.005 - 22.4 mmol (up to ~2 g of resin per RV)
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Reaction Vessels:
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24 - glass (10, 40 mL) or disposable plastic (10, 45 mL)
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Chemistry:
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Solid phase synthesis (e.g. peptide, peptoid, PNA, DNA, combinatorial, small organic molecules)
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Activation Schemes:
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In-situ; pre-activation; experimental
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Reagents/Solvents:
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Eight pressurized solvents (0.5 to 20 L each)
Up to 40 amino acid positions (10, 120 or 400 mL bottles)
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Fluid Measurement:
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Precalibrated PTFE tubing
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Solution Transfer:
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Nitrogen or Argon pressure
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Solution Removal:
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Filtration
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Waste Containers:
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(20 L) with float switches
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Agitation:
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Adjustable sparging
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Computer:
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PC , MS Windows based
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Interface:
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RS232
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Power:
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105-125/210-250 volts, 50/60 Hz
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Dimensions:
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45 inch Wide x 66 inch Height x 29 inch Depth
(114 cm W x 168 cm H x 74 cm D)
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Warranty:
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One year, parts and labor
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Features:
Infrared (IR) Heating
Now you can get the most efficient heating method on the market today! With the fastest time to temperature of any heating technology, infrared heating can be performed on more than one reaction vessel at a time. It is also fully-compatible with vortex mixing, so you can be sure you have an even temperature profile. Other heating systems use nitrogen mixing, which may result in hot and cold spots and effect the consistency of your chemistry.
Real-Time UV-Monitoring
Minimize trial-and-error when synthesizing difficult peptides using real-time UV monitoring on the Symphony X. What makes our UV monitoring different? Other systems just monitor the waste stream. We monitor your reaction solution while it’s mixing – that’s why we’re the only ones who can control the deprotection reaction times, not just the number of repetitions!
Preactivation
Now you can preactivate on multiple reactors in parallel. Perfect for sterically hindered amino acid additions! Optimize your DIC/HOBt chemistry on the Symphony X and go straight to scale-up!
Special Reagent Additions
At last! Add expensive special reagents to any reactor without priming or wasting a drop using Single-Shot deliveries! Save money with no manual intervention required! The Symphony X comes with up to 40 amino acid positions to accommodate any chemistry!
Reliability – the PTI difference
Other systems use off-the-shelf valves that leak, cross-contaminate, and quickly fail when exposed to harsh peptide synthesis chemicals. Our patented valve block system was specifically designed for peptide synthesis, so you get zero dead volumes, no cross-contamination, and worry-free performance that lasts for years!
Fully Independent Channels
The Symphony is the world’s first peptide synthesizer with fully independent channels. This means you can run different sequences, scales and protocols on multiple reactors all at the same time. Start, Stop or Pause reactors whenever you wish! It’s like having 24 synthesizers in one!
Automated Cleavage
The Symphony X features automated cleavage. Unlike some peptide synthesizers, all PTI synthesizers are built with robust TFA-resistant materials, so you can cleave for years on our instruments without worry. Not interested in cleavage? You can also use the Symphony X collect positions as additional amino acid positions!
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