The Sonata™ mid-scale peptide synthesizer is specifically designed for automated solid phase synthesis of gram to near kilogram quantities of peptide with a multitude of solvents. All reactions occur in an inert environment to minimize side reactions. Seven solvent ports and twenty reagent ports allow easy customization of any synthesis protocol. Several fluid-filling methods and mixing modes can be selected to optimize performance. To minimize disposal costs, two waste ports allow waste streams to be separated. A collection port can be implemented for cleavage product or valuable reagent recovery for maximum versatility. Automated continuous monitoring of all system requirements, solvents, waste tanks, and fluid transfer assures fail-safe operation.
Features:
Flexible Methods and Modes
The Sonata™ has chemically inert, optimized channels allowing high solution transfer rates (> 400 mL/min) of any solvent. All reactions occur in an inert environment to minimize side reactions. Multiple mixing modes including sparging, recirculation and mechanical agitation which can be combined to maximize reaction efficiency. Several fluid-filling methods can be selected to optimize performance.
Ideal for Custom Chemistry Requirements
Seven solvent ports and twenty reagent ports allow easy customization for any synthesis protocol. Two volumetric vessels allow precise aliquots of all solvents/reagents to be delivered. To minimize disposal costs, two waste ports allow waste streams to be separated. A collection port can be implemented for cleavage product or valuable reagent recovery for maximum versatility.
Simple Software
Versatile, easy to use Windows-based software allows the experienced chemist or novice operator complete control of all aspects of synthesis. Complete documentation of all operations occurs once synthesis is initiated.
Proven Reliability
The Sonata™ uses the same patented matrix valve components as the Symphony® Peptide Synthesizer which has proven to be extremely reliable in the field since its introduction in February 1993. Automated continuous monitoring of all system requirements, solvents, waste tanks, and fluid transfer assures fail-safe operation.
Specifications:
|
Synthesis Scale:
|
|
0.25 - 100.0 mmol (up to 212 grams of resin)
|
|
|
Reaction Vessels:
|
Standard sizes: 200, 500, 2000 mL
Custom sizes available
|
|
Chemistry:
|
Solid phase synthesis (e.g. peptide, combinatorial, small organic molecules)
|
|
Activation Schemes:
|
In-situ; pre-activation; experimental
|
|
Reagents/Solvents:
|
One pumped solvent (1 to 200 L supply)
Six pressurized solvents (0.5 to 20 L each)
Twenty additional reagents (0.25 L each)
|
|
Fluid Measurement:
|
Two interchangeable volumetric vessels;
fill by time or
fill to top of reaction vessel
|
|
Solution Transfer:
|
Nitrogen or Argon pressure
(a pump is used for the primary solvent)
|
|
Solution Removal:
|
Filtration
|
|
Waste Containers:
|
Two (20 L standard; 200 L optional) with float switches
|
|
Agitation:
|
Adjustable sparging; recirculation; variable oscillation.
|
|
Computer:
|
PC, MS Windows based |
|
Interface:
|
RS232
|
|
Power:
|
105-125/210-250 volts, 50/60 Hz |
|
Dimensions:
|
35 inch Wide x 60 inch Height x 24 inch Depth
(81.3 cm W x 153 cm H x 61 cm D)
|
bio-equip.cn
中文
