Trace amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a class of G protein-coupled receptors that were discovered in 2001.TAAR1, the first of six functional human TAARs, has gained considerable interest in academic and proprietary pharmaceutical research due to its unique role as the endogenous receptor for trace amines – which are trace metabolic derivatives of phenylalanine and tryptophan – and related psychostimulants, particularly amphetamine and methamphetamine. In 2004, it was shown that mammalian TAAR1 is also a receptor for thyronamines, which are decarboxylated and deiodinated metabolites of thyroid hormones.TAAR2–TAAR9 function as olfactory receptors for volatile amines in vertebrates.
Mouse Putative trace amine-associated receptor 3 (TAAR3) ELISA Kit employs a two-site sandwich ELISA to quantitate TAAR3 in samples. An antibody specific for TAAR3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTAAR3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TAAR3 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TAAR3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Mouse Putative trace amine-associated receptor 3 (TAAR3) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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