ChIP Validated Antibodies
The use of high quality and specific ChIP validated antibodies is essential for the success of a ChIP assay. The antibody must recognise and bind to native protein that is bound to DNA. Antibodies from other applications do not always work well in ChIP.
Anti H3K14ac, Clone RM130
Product Code : 700012
Histone 3 (H3) is one of the core histone proteins, comprising the protein component of chromatin. H3 is ubiquitous within chromosomes and can be found bound to most gene sequences throughout the genome. Acetylation of histone H3 occurs at several different lysine positions on the histone tail and is catalysed by a group of enzymes called histone acetyltransferases (HATs). The histone acetylation mark H3K14ac can indicate enhancer sites; helping to identify active enhancers from poised ones. H3K14ac is associated with active transcription and can be found at the start site of actively transcribed genes.
This antibody recognises an acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys 14).
•Applications: ChIP, WB, ELISA, Multiplex
•Source: Rabbit
•Concentration: 1mg/ml
•Type: Monoclonal
Size: 100μl
•Purification: Protein A (affinity purified)
•Specificity: Human
•Storage: +2- +8°C
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