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Illumina Introduces the NovaSeq Series鈥攁 New Architecture Designed to Usher in the $100 Genome

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High Throughput Sequencing Instruments Capable of Transforming Genomics to Improve Human Health at an Unprecedented Scale
 
SAN DIEGO--(BUSINESS WIRE)--Jan. 9, 2017-- Illumina, Inc. (NASDAQ: ILMN), the global leader in next-generation sequencing technology, today introduced the NovaSeqTM Series, a new and scalable sequencing architecture expected one day to enable a $100 genome. Unveiled at the J.P. Morgan Healthcare Conference, this platform redefines high throughput sequencing with unrivaled throughput, ease of use, low per sample costs, and unmatched flexibility.
Illumina NovaSeq 6000 System (Photo: Business Wire)
 
NovaSeq is the most powerful sequencer Illumina has ever launched and will open new horizons for more highly powered experiments at the depth required to discover rare genetic variants. It was designed from the ground up to allow a broad set of researchers to access next-generation sequencing technology and more easily conduct large-scale genomics projects with greater sample volumes, or more breadth and depth in the genome. In addition to a single instrument capable of sequencing from three to 48 human whole genomes per run, the NovaSeq Systems will open up new markets by making routine a wide range of applications from ultra-deep sequencing of matched tumor-normal pairs, to large-scale variant discovery studies associated with complex diseases, and low-pass sequencing of seed banks to select for specific traits.
 
鈥淲e are excited to be among the first to incorporate Illumina鈥檚 new NovaSeq System into the HLI sequencing center to complement our existing HiSeq X® Systems,鈥 said J. Craig Venter, PhD, Co-founder and Executive Chairman of Human Longevity Inc. 鈥淔aster, inexpensive and innovative sequencing technology is a key component driving breakthroughs in precision medicine. This technology is also enabling HLI to expand the HLI database, the world鈥檚 most comprehensive database of genomic, phenotypic, and clinical data.鈥
 
鈥淣ovaSeq is a key development for clinical research,鈥 said Richard Gibbs, Founder of the Baylor College of Medicine Human Genome Sequencing Center. 鈥淲e are looking forward to generating tens of thousands of human whole genomes as we begin genome translation in earnest.鈥
 
鈥淭he Regeneron Genetics Center has sequenced more than 150,000 exomes in the last few years and we anticipate that moving to the NovaSeq platform will further increase our efficiency and output,鈥 said Aris Baras, MD, Head, Regeneron Genetics Center. 鈥淲e believe that genetic insight is critical to informing and advancing new treatments and are committed to expediting these advances for patients.鈥
 
鈥淭he introduction of NovaSeq marks one of the most important inflection points of innovation in Illumina鈥檚 history. In the same way that HiSeq X enabled the $1,000 genome with the HiSeq® architecture first announced in 2010, we believe that future systems derived from the NovaSeq architecture we are launching today one day will enable the $100 genome and propel discoveries that will enable a deeper understanding and better treatments for complex disease,鈥 said Francis deSouza, President and CEO of Illumina. 鈥淭he NovaSeq Systems enable the study of genetic links between health and disease at an unprecedented scale by making it possible to sequence more samples at greater depth and take on projects that would otherwise be cost-prohibitive. By accelerating the trajectory of genomics with these systems, Illumina is making it possible to envision a future in which all people can benefit from precision medicine.鈥
 
The NovaSeq Series includes the NovaSeq 5000 and 6000 Systems. These instruments offer ease of use features similar to those found in Illumina鈥檚 desktop sequencing portfolio, including automated onboard cluster generation, cartridge-based reagents, and streamlined workflows. With scalable throughput, users will have the flexibility to perform sequencing applications requiring different levels of output by simultaneously running one or two flow cells from up to four different flow cell types.
 
The NovaSeq 5000 and 6000 Systems are priced at $850,000 and $985,000 respectively. Compared with other Illumina sequencing systems, both have lower per sample consumable costs for most sequencing applications. They provide laboratories that cannot afford the capital cost of a HiSeq X Five or HiSeq X Ten System with a roadmap to completing human whole-genome sequencing projects at a cost of $1,000 per genome.
 
The NovaSeq 6000 will begin shipping in March 2017 and NovaSeq 5000 will begin shipping mid-2017. For more information, visit www.illumina.com/novaseq.
 
For Research Use Only. Not for use in diagnostic procedures.
 
About Illumina
 
Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as the global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit www.illumina.com and follow @illumina.
 
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Illumina, Inc.
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